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Of significance to renal function is the fact that the WNK kinases, particularly WNK1 and WNK4, regulate the activity of several ion transporters

GGT activity was calculated by obtaining the slope of the linear range of each sample (Abs per min) and dividing by the slope of a 4-nitroaniline standard curve (Abs per nmoles pNA) and by the protein mass (mg) to determine the reaction rate of the sample (nmoles pNA min 1 mg 1 )

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in addition, it has been demonstrated that RBM45 can bind p62 and that RBM45-p62 cytoplasmic colocalization was increased in ALS spinal cords [247]